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VOLUME 6 , ISSUE 3 ( July-September, 2020 ) > List of Articles

CASE REPORT

Mucoepidermoid Carcinoma: Presentation at an Uncommon Site

Arpit Mago

Keywords : Case report, Mucoepidermoid carcinoma, Salivary gland

Citation Information : Mago A. Mucoepidermoid Carcinoma: Presentation at an Uncommon Site. J Med Sci 2020; 6 (3):51-53.

DOI: 10.5005/jp-journals-10045-00156

License: CC BY-NC 4.0

Published Online: 29-09-2021

Copyright Statement:  Copyright © 2020; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Introduction: Mucoepidermoid carcinoma represents about 15% of salivary gland tumors. They occur mainly in the parotids (60–70%) but they account for a large fraction of salivary gland tumors in the minor salivary glands. Overall they are the most common form of primary malignant tumor of the salivary glands. Our report exemplifies the need to evaluate swellings of the neck region meticulously as it might not be just an inflammatory swelling but an indication of malignancy. Case report: A 36-year-old male patient was referred to our hospital for evaluation of a swelling in the upper neck which gradually progressed over a span of 3 months. It was painless, firm in consistency, and ovoid in shape. The blood and urine investigations were normal. Fine needle aspiration cytology (FNAC) was performed and the findings were correlated with IHC and the mass was confirmed to be a mucoepidermoid carcinoma. Discussion: Mucoepidermoid carcinomas show variability in their behavior. The prognosis is dependent on the clinical stage, site, grading. Duration before diagnosis ranges from months to years. The cure is possible in low and intermediate grades of tumors. Characteristically, it shows t[11;19][q21;p13] with MET1–MAML2 fusion in other cases it occurred in the parotid gland and palate. This is probably the first case reported to occur in a submandibular gland in a patient in the third decade of his life, with its incidence normally common in the 5th to 6th decade.


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  1. Sando Z, Fokouo JV, Mebada AO, et al. Epidemiological and histopathological patterns of salivary gland tumors in Cameroon. Pan Afr Med J 2016;23:66. DOI: 10.11604/pamj.2016.23.66.5105.
  2. Loury MC. Salivary gland disorder. Adv Otolaryngol 2000.
  3. Spiro RH. Salivary neoplasms: overview of a 35-year experience with 2807 patients. Head Neck Surg 1986;8(3):177–184. DOI: 10.1002/hed.2890080309.
  4. Ostman J, Anneroth G, Gustafsson H, et al. Malignant salivary gland tumours in Sweden 1960-1989: an epidemiological study. Oral Oncol 1997;33(3):169–176. DOI: 10.1016/s0964-1955(96)00077-2.
  5. Cornog JL, Gray SR. Surgical and clinical pathology of salivary gland tumors. In: Rankow RM, Polayes IM, ed. Disease of the salivary glands. Philadelphia, Pa: WB Saunders Co; 1976. 99–142.
  6. Pires FR, Chen SY, Da Cruz Perez DE, et al. Cytokeratin expression in central mucoepidermoid carcinoma and glandular odontogenic cyst. Oral Oncol 2004;40(5):545–551. DOI: 10.1016/j.oraloncology.2003.11.007.
  7. Qureshi SM, Janjua OS, Janjua SM. Mucoepidermoid carcinoma: a clinico-pathological review of 75 cases. Int J Oral Maxillofac Pathol 2012;3:5–9.
  8. Rupani AB, Kavishwar VS, Achinmane V, et al. Fine needle aspiration cytology of low-grade mucoepidermoid carcinoma of the parotid gland: a diagnostic challenge. J Cytol 2008;25(3):115–116. DOI: 10.4103/0970-9371.44051.
  9. Joseph TP, Joseph CP, Jayalakshmy PS, et al. Diagnostic challenges in cytology of mucoepidermoid carcinoma: report of 6 cases with histopathological correlation. J Cytol 2015;32(1):21–24. DOI: 10.4103/0970-9371.155226.
  10. Al-Khafaji BM, Nestok BR, Katz RL. Fine-needle aspiration of 154 parotid masses with histologic correlation-ten-year experience at the university of Texas M. D. Anderson cancer center. Cancer Cytopathol 1998;84(3):153–159. DOI: 10.1002/(SICI)1097-0142(19980625)84:3<153::AID-CNCR6>3.0.CO;2-P.
  11. Stewart FW, Foote FW, Becker WF. Muco-epidermoid tumors of salivary glands. Ann Surg 1945;122(5):820–844. DOI: 10.1097/00000658-194511000-00005.
  12. Nagao T, Sato E, Inoue R, et al. Immunohistochemical analysis of salivary gland tumors: application for surgical pathology practice. Acta Histochem Cytochem 2012;45(5):269–282. DOI: 10.1267/ahc.12019.
  13. Bradley PJ. Distant metastases from salivary glands cancer. ORL J Otorhinolaryngol Relat Spec 2001;63(4):233–242. DOI: 10.1159/000055748.
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