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VOLUME 5 , ISSUE 3 ( July-September, 2019 ) > List of Articles

Original Article

Analysis of Distribution of Allergens and its Seasonal Variation in Allergic Rhinitis

Kammili Jyothirmayi

Keywords : Allergens, Allergic rhinitis, Dust mite, Seasonal

DOI: 10.5005/jp-journals-10045-00129

License: CC BY-NC 4.0

Published Online: 15-07-2020

Copyright Statement:  Copyright © 2019; The Author(s).


Abstract

Introduction: Allergic diseases are common and they have increased in frequency over the last few decades. More than 30% of the population suffers from allergic rhinitis (AR). It is defined as a combination of two or more symptoms, namely, watery rhinorrhea, nasal obstruction, itching, and sneezing. Allergic rhinitis occurs when these symptoms are the result of immunoglobulin E (IgE)-mediated inflammation following exposure to allergens. The common inhalant allergens causing AR are house dust mites, pollens, fungi, and insects. Skin prick test (SPT) is the gold standard test in the diagnosis of AR. Aim: To study the distribution of inhalant allergens in AR and to find out seasonal variations in allergens by SPT. Materials and methods: A descriptive study was done in 120 patients who came with symptoms of AR to ear, nose, and throat (ENT) outpatient department (OPD) of tertiary care hospital. The study was done from November 2017 to October 2018. The patient was clinically evaluated and the SPT was performed to analyze the distribution of inhalant allergens and its seasonal variations. Results: The majority of the patients are males between 21 and 30 years of age. Majority of the people are urban residents. Dust mites followed by pollens yielded the highest number of positive responses among inhalant allergens. Dust mites and dusts are more common during winter season, pollens are more common during summer season, and fungi and insects (5.83%) during rainy season. Conclusion: Analyzing the distribution of specific allergens for a particular geographical area and its seasonal variation helps in appropriate diagnostic evaluation of allergens, educating the patient on what allergen to avoid and also to find the best formulation of allergen immunotherapy for effective AR treatment.


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  1. Konuk S. Skin prick test in allergic rhinitis in Duzce province of Turkey. Biomed Res 2017;28(15).
  2. Mahram M, Barikani A, Nejatian N. The frequency of common allergens in allergic rhinitis among the patients Referred to the allergy clinic of Qods hospital in Qazvin during 2007-2010. J Aller Ther 2013;4:130. DOI: 10.4172/2155-6121.1000130.
  3. University A analyst at PG is M in PS has worked as an AP in PBDS, Drugs is a published research scholar S has worked on several Projects like A-U, Formulations SR, books FTFH lies in, writing, Travel SL to, et al. Prevalence allergic rhinitis and its diagnosis with therapeutic considerations [Internet]. Knowledge Tank. 2017 [cited 2019 Oct 24].
  4. Bousquet J, Bousquet PJ, Godard P, et al. The public health implications of asthma. Bull World Health Organ 2005;83(7):548–554.
  5. Weinmann S, Kamtsiuris P, Henke KD, et al. The costs of atopy and asthma in children: assessment of direct costs and their determinants in a birth cohort. Pediatr Allergy Immunol 2003;14(1):18–26. DOI: 10.1034/j.1399-3038.2003.02085.x.
  6. Samolinski B, Sybilski AJ, Raciborski F, et al. Prevalence of rhinitis in polish population according to the ECAP (epidemiology of allergic disorders in Poland) study. Otolaryngol Pol 2009;63(4):324–330. DOI: 10.1016/S0030-6657(09)70135-0.
  7. Lobo F, Lobo B. Quality of life in asthmatic outpatients. J Asthma 2008;45:27–32. DOI: 10.1080/02770900701815495.
  8. Wang DY. Risk factors of allergic rhinitis: genetic or environmental? Ther Clin Risk Manag 2005;1(2):115–123. DOI: 10.2147/tcrm.1.2.115.62907.
  9. Violeta VB, Naser B, Besa L, et al. Sensitivity to pollen allergens in consecutive patients with allergic rhinitis referred to an allergy clinic in Prishtina. Mac J Med Sci 2010;2:121–125.
  10. Asha'ari ZA, Yusof S, Ismail R, et al. Clinical features of allergic rhinitis and skin prick test analysis based on the ARIA classification: a preliminary study in Malaysia. Ann Acad Med Singapore 2010;39(8):619–624.
  11. Schoenwetter WF. Allergic rhinitis: epidemiology and natural history. Allergy Asthma Proc 2000;21(1):1–6. DOI: 10.2500/108854100778248971.
  12. Ciprandi G, Pistorio A, Tosca M, et al. Body mass index, respiratory function and bronchial hyperreactivity in allergic rhinitis and asthma. Respir Med 2009;103(2):289–295. DOI: 10.1016/j.rmed.2008.08.008.
  13. Nilsson L, Castor O, Löfman O, et al. Allergic disease in teenagers in relation to urban or rural residence at various stages of childhood. Allergy 1999;54(7):716–721. DOI: 10.1034/j.1398-9995.1999.00896.x.
  14. Sharma R, Gaur SN, Singh VP, et al. Association between indoor fungi in Delhi homes and sensitization in children with respiratory allergy. Med Mycol 2012;50(3):281–290. DOI: 10.3109/13693786.2011.606850.
  15. Choi IS, Ki WJ, Kim TO, et al. Seasonal factors influencing exercise-induced asthma. Allergy Asthma Immunol Res 2012;4(4):192–198. DOI: 10.4168/aair.2012.4.4.192.
  16. Kim E, Kim MJ, Lee JS, et al. Association between autumnal exacerbation and dermatophagoides pteronyssinus specific IgE in childhood asthma. Pediatr Allergy Respir Dis 2007;17:242–248.
  17. Arbat A, Tirpude S, Dave MK, et al. Purview of allergens through skin test in Central India. Environ Dis 2016;1(3):99–104. DOI: 10.4103/2468-5690.191983.
  18. Kumar R, Kumar M, Bisht I, et al. Prevalence of aeroallergens in patients of bronchial asthma and/or allergic rhinitis in India basedon skin prick test reactivity. Indian J Allergy, Asthma and Immuno 2017;31(2):45–55. DOI: 10.4103/ijaai.ijaai_23_17.
  19. Dave L, Srivastava N. A study of sensitization pattern to various aeroallergens by skin prick test in patients of united airway disease (UAD) in Bhopal, Madhya Pradesh, India. RJPBCS 2014;5(4):1397.
  20. Gill NK, Singh A, Dhaliwal AK, et al. House dust mites and pollens as risk factors in allergic manifestations. Indian J Sci Res 2016;7(1):131–142.
  21. Anonymous: All India Coordinated Project on Aeroallergens and Human Health. Report. Ministry of Environment and Forests, New Delhi; 2000.
  22. Singh AB, Kumar P. Common environmental allergens causing respiratory allergy in India. Indian J Pediatr 2002;69(3):245–250. DOI: 10.1007/BF02734234.
  23. Subbarao M, Prakash O, Subba Rao PV. Reaginic allergy to parthenium pollen: evaluation by skin test and RAST. Clin Allergy 1985;15(5): 449–454. DOI: 10.1111/j.1365-2222.1985.tb02294.x.
  24. Agrawal RL, Chandra A, Jain S, et al. Identification of common allergens by skin prick test associated with United airway disease in Allahabad, Uttar Pradesh, India. Indian J Allergy Asthma Immunol 2008;22:7–13.
  25. Gaur SN, Kapoor MK, Garg DC, et al. Etiological significance of insects in nasobronchial allergy. Aspects Allergy Appl Immunol 1985;18:19–27.
  26. Acharya PJ. Skin test response to some inhalant allergens in patients of nasobronchial allergy from Andra Pradesh. Aspects Allergy Appl Immunol 1980;8:34–36.
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