A nonhealing ulcer is defined as an ulcer that does not heal even after 13 weeks of constant treatment. The treatment of this condition causes the patient a great economic and mental burden. Even with the widely available treatment modalities, the treating doctor faces the challenge to give significant results at a low-cost. Here, we report three cases and explore platelet-rich fibrin matrix (PRFM), a low-cost yet effective modality treatment cornerstone for nonhealing ulcers.
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