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VOLUME 6 , ISSUE 2 ( April-June, 2020 ) > List of Articles


Nicolau Syndrome: A Rare Adverse Effect of Intravenous Diclofenac Sodium Injection

Kanchan Kumawat, Mohammad Rafi, Chaitanya Namdeo, Chhaya Goyal

Keywords : Embolia cutis medicamentosa, Nicolau syndrome, Parenteral injection

Citation Information : Kumawat K, Rafi M, Namdeo C, Goyal C. Nicolau Syndrome: A Rare Adverse Effect of Intravenous Diclofenac Sodium Injection. J Med Sci 2020; 6 (2):32-33.

DOI: 10.5005/jp-journals-10045-00143

License: CC BY-NC 4.0

Published Online: 01-06-2020

Copyright Statement:  Copyright © 2020; The Author(s).


Nicolau syndrome (embolia cutis medicamentosa) is an uncommon complication of intramuscular injection leading to necrosis of skin and underlying tissue to a variable extent. I am reporting one such case who developed this complication after intravenous injection of diclofenac sodium. The aim of reporting this case is to create awareness among our colleagues and staff to exercise precautions during parental injection administration.

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