The Journal of Medical Sciences

Register      Login

VOLUME 5 , ISSUE 1 ( January-March, 2019 ) > List of Articles


Anesthetic Management of Pheochromocytoma

Kattani Shyamprasad Amod, Faizya Taskeen, KT Venkatesh Murthy, Hiremathada Sahajananda

Keywords : Catecholamines, Hypertension, Hypertensive crises, Pheochromocytoma

DOI: 10.5005/jp-journals-10045-00103

License: CC BY-NC 4.0

Published Online: 01-03-2019

Copyright Statement:  Copyright © 2019; The Author(s).


Pheochromocytomas (PCCs) are rare neuroendocrine tumors originating from the chromaffin tissue.1 These tumors produce, store, and secrete catecholamines. Most PCCs produce both epinephrine and norepinephrine, with the percentage of secreted norepinephrine being greater than that secreted by the normal gland.2 The incidence of PCCs is 2 to 8 per 1 million populations per year. They are highly vascular and catecholamine-producing tumors. They are derived from the sympathetic or parasympathetic nervous system. It is estimated that 0.1% of all hypertensives may have neuroendocrine tumors like PCC. In these patients, usual presenting signs and symptoms are tachycardia, hypertension, etc.,3 which are the result of sympathetic stimulation. The literature also shows a high prevalence of familial and extra adrenal tumors in patients carrying germline mutations in genes.1 It may be as high as 50%.1 Surgery and anesthesia in these patients pose a high risk of cardiovascular complications from hypertensive crisis. Here, we report a case of PCC scheduled for surgical resection.

  1. Ramakrishna H. Pheochromocytoma resection: current concepts in anesthetic management. J Anaesthesiol, Clin Pharmacol 2015 Jul;31(3):317. DOI: 10.4103/0970-9185.161665.
  2. Barash textbook clinical anesthesia, 7th ed. Wolters Kluwer India Private Limited, 1 December 2017; pp.1339.1342.
  3. Suryawanshi C, Thatte WS, et al. Anesthetic management of a missed pheochromocytoma during exploratory laparotomy. Anaesth, Pain Intensive Care 2019 Feb 3:296.298.
  4. Roizen MF. A prospective randomized trial of four anesthetic techniques for resection of pheochromocytoma. Anesthesiology 1982;57: A43.
  5. Basu M, Gupta SD, et al. Anaesthetic management of bilateral phaeochromocytoma in a young female patient. Indian J Anaesth 2007 May 1;51(3):237.
  6. Prys-Roberts C. Phaeochromocytoma. recent progress in its management. Br J Anaesth 2000 Jul 1;85(1):44.57.
  7. Gupta P, Gogia AR, et al. Anaesthetic management of bilateral phaeochromocytoma in a child. a case report. Indian J Anaesth 2005 Jan 1;49(1):54.55.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.