Clinicopathological Study of Testicular Tumors
PS Sharmila, Ashwin P Surhonne, Alka V Gosavi, Shobhana R Agashe, Molly A Phansopkar
Germ cell tumor, Testicular tumor, Testis,Frequency
Citation Information :
Sharmila P, Surhonne AP, Gosavi AV, Agashe SR, Phansopkar MA. Clinicopathological Study of Testicular Tumors. J Med Sci 2018; 4 (3):63-70.
CC BY-SA 4.0
Copyright © 2018; Jaypee Brothers Medical Publishers (P) Ltd.
Objective: Clinicopathological analysis of testicular tumors as per World Health Organisation (WHO) classification.
Materials and methods: All consecutive cases of testicular tumors diagnosed in the department of pathology for five year were included in this study.
Results: During the span of five years, total 59 cases of testicular tumors were diagnosed. Scrotal mass or swelling was the predominant mode of presentation. Germ cell tumors constituted 89.8% (n = 53) of all testicular neoplasms in which seminoma 32.2% and teratocarcinoma 13.4% were present. Yolk-sac tumor (5.1%) was the commonest testicular neoplasm in children while lymphoma (8.5%) was the predominant neoplasm in elderly population. One case of leukemic infiltration of testis (1.7%) in a known patient of acute lymphocytic leukemia after chemotherapy was also observed.
Conclusion: In this study clinical presentation, age, and frequency of testicular tumors, with few exceptions are similar to other studies from different parts of country, confirming similarity in international literature.
Garner M.J., Turner MC, Ghadirian P, Krewski D: Epidemiology of testicular cancer: an overview: Int. J. Cancer: 2005; 116:331-339.
Epstein JI. The Lower Urinary Tract and Male Genital system, Testis and Epididymis. Robbins Pathologic basis of disease. 8th ed., Philadelphia. WB :2010, Ch.21:984-986.
Tick SK, Amin MB, Crarner HM, Lara R Uibright TM. The testis, paratesticular structures and male external genialia ; Silverberg’ principles andpractice of surgical pathology and cytopathology. 4th edition: Churchiillivingstone: 2004, vol 2: Ch.34.
Dixon, FJ, Moore, RA: Tumors of the male sex organs. p. 45. Atlas of human pathology. Section 8, Fascicles 31 and 32. Armed Forces Institute of Pathology, Washington 1952.
Young. RH, Clement PB, Scully RE, The fallopian tube and broad ligament. In: Sternberg's diagnostic surgical pathology. Mills SE (ed.) 4th edition, Philadelphia, Lippincott Williams and Wilkins, 2004; vol 3: Chapter 57.
Mostofi FK, Price EB Jr. tumors of male genital system. Atlas of tumor Pathology series 2 Fascicle and armed forces institute of Pathology. Washington DC 1973.
Mostofi FK Sabin LH Histological typing of testis tumors. International Histological classification of tumors No. 16 WHO Geneva 1977.
Baade P, Carriere P, Fritschi L. Trends in testicular germ cell cancer incidence in Australia. Cancer Causes Control 2008; 19: 1043.
Shaw J. Diagnosis and treatment of testicular cancer. Am Fam Physician 2008, 77:469.
Shinagare AB, Jagannathan JP, Ramaiya NH, Hall MN, Van den Abbeele AD. Adult extragonadal germ cell tumors. AJR 2012, 195, 274.
Tongaonkar H. Testicular cancer: Current management and controversial issues. Indian J Urol 2010, 26, 63.
Rosai J. Male reproductive system. Rosai and Ackerman's Surgical pathology. 10th edition Mosby Elsevier, 2011:vol1: ch.18:1338-1362.
Chandanwale S, Chawala R, Buch A, Dharawadkar A, Gore C, Rajpal M. Pathology of testis. Int J Pharm Biomed Sci. 2012, 3(4), 167-176.
Fischer CG, Waechter W, Kraus S, Perez EF, Weidner W, Dudeck J. Urologic tumors in the Federal Republic of Germany. Cancer 1998, 82, 775.
Gupta VP, Chopra HL. Nagpal 8 L. Tumors of tee-tis. Ind. J. Pathol Microbiology. 1980:23:155-160.
Gupta SC, Sharma A. et al. Testicular tumors (A clinicopathological study) Ind. J. Surgery.1983;45: 664-672.
Deotra A, Mathur DR, Vyas MC. A 18 years study of testicular tumors in Jodhpur, western Rajasthan. J Postgrad Med 1994;40:68-70.
Mostofi FK, David CJ. Male reproductive system and prostate. Kissane JM. Anderson's Pathology. 8thEdn. St. Louis Mosby, 1985; 798-800.
Moghe KV, Aggrawal RV, Junnarkar RV. Tumors of the testis. Ind, J. Cancer.1970;7:90-97.
Miller A, Selielid P. Histopathologic classification and natural history of malignant testis tumors in Norway. Cancer 1971; 26;1:1054-1062.
Collins DH, Pugh RCB. Classification and frequency of testicular cancer. Br J Urol 1964, 36 (suppl 1), 1-11.
Damjanov I. Tumors of the testis and epididymis in Murphy W.M. (ed). Urologic Pathology Philadelphia 1989, 314-379.
Aggrawal PK, Wabal KM., Mehrotra RML. Testicular tumors in infancy and childhood. Indian J. Pathol Micro, 1976, 75-84.
Shivade AV Kher AV et al. choriocarcinoma of testis. Report of 2 cases and review of literature. Indian J. Cancer: 1972, 75-78
Bergner DM. Duck GB. Rao M. Bilateral sequential spermatocytic seminoma. J. Urology 1980,12:565-566.
Schoberg TW Wittakar3. et al. Metastaticspermatocytic seminoma, J. Urology;1980:124:739-741.
Mechrotra RML. Wahal KM, Aggrawal PK. Testicular lymphoma. A clinicopathological study of 22 cases. Ind. J. Pathol Microbiology:1979;22:301-306.