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VOLUME 4 , ISSUE 1 ( January-March, 2018 ) > List of Articles

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Comparison of High-flow Oxygen Therapy using Nasal Canula with Standard Oxygen Therapy using Face Mask in Patients with Acute Hypoxemic Respiratory Failure

Suheib Muneer, Srinivasan Rangalakshmi

DOI: 10.5005/jp-journals-10045-0079

License: NA

Published Online: 01-12-2013

Copyright Statement:  NA


Abstract

Introduction: High-flow oxygen therapy through nasal cannula is a technique whereby heated and humidified oxygen is delivered to nose at high flow rates and this generates low levels of positive pressure in upper airways. This may decrease physiological dead space by flushing expired CO2 from the upper airway, a process that explains the decrease in the work of breathing. With this we determine whether high-flow oxygen therapy as compared with standard oxygen therapy alone could reduce the rate of endotracheal intubation and outcomes. Materials and methods: We performed a prospective randomized trial in our intensive care unit (ICU), in which we randomly assigned patients with acute hypoxemic respiratory failure without hypercapnia into two groups. A total 30 patients were taken in our study and were randomly allocated to groups I and II (15 in each group) with type I r espiratory failure. • Group I: Received high-flow oxygen therapy using nasal cannula • Group II: Treated with standard oxygen mask therapy The outcome of two groups was compared in terms of PaO2 and the proportion of patients who needed reintubation. Results: Demographic data (Table 1) were not significant between the two groups. Arterial blood gas (ABG) analysis (Table 2) showed PaO2 of 92 + 32 mm Hg in high-flow nasal oxygen (group I) receiving patients compared with PaO2 of 85 ± 31 mm Hg in standard oxygen therapy patients (group II). The intubation rate (Table 2) was 46% (7/15) in highflow nasal oxygen group (I) and 66% (10/15) in the standard oxygen therapy group (II). Conclusion: Patients with nonhypercapnic acute hypoxemic respiratory failure treatment with high-flow nasal oxygen have significantly better outcome compared with oxygen therapy with the standard oxygen therapy with face mask.


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