The Journal of Medical Sciences

Register      Login

VOLUME 3 , ISSUE 2 ( April-June, 2017 ) > List of Articles

ORIGINAL ARTICLE

Study of Prevalence of Hypomagnesemia in Patients with Type II Diabetes Mellitus

NH Rekha, MS Bharath, SP Channakeshava

DOI: 10.5005/jp-journals-10045-0057

License: NA

Published Online: 01-01-2017

Copyright Statement:  NA


Abstract

Introduction

Diabetes mellitus is a common metabolic disorder. Prevalence of diabetes is increasing globally and it is one of the major health problems of the 21st century. The disturbance in serum magnesium (SMg) has been reported among patients with type II diabetes mellitus. Hypomagnesemia has negative impact on glucose homeostasis and insulin sensitivity in patients with type II diabetes mellitus.

Aim

This study was undertaken to know the prevalence of hypomagnesemia in patients with type II diabetes mellitus and its relation with glycated hemoglobin (HbA1c). The study was conducted on 200 patients with type II diabetes and 100 healthy controls at RajaRajeswari Medical College & Hospital, Bengaluru.

Results

Out of 200 diabetic patients, 115 (57%) had hypomagnesemia. We observed mean SMg (1.7 mg) significantly low in diabetic patients compared with controls (2.1 mg). We also found HbA1c was high (9%) in hypomagnesemia patients. We found that diabetic hypomagnesemic patients had high mean fasting blood glucose (242.6 mg%) and postprandial blood sugar (313 mg%) than controls.

How to cite this article

Rekha NH, Bharath MS, Channakeshava SP. Study of Prevalence of Hypomagnesemia in Patients with Type II Diabetes Mellitus. J Med Sci 2017;3(2):55-58.


HTML PDF Share
  1. Epidemiology of diabetes in developing countries. The scenario in Asia. In: Snehalatha C, Nanditha A, editors. RSSDI textbook of diabetes mellitus. 3rd ed. New Delhi: Jaypee; 2012. vol 1, p. 142-149.
  2. Hypomagnesemia in patients with diabetes mellitus. World Appl Sci J 2011;12(10):1803-1806.
  3. Magnesium deficiency and diabetes mellitus. Curr Sci 2002 Dec;83(12):1456-1463.
  4. Hypomagnesemia in diabetes. Postgraduate Med J 1992;92:1180-1195.
  5. Study of serum magnesium and HbA1c in type 2 diabetes mellitus patients. Int J Sci Res 2015 Jun;4(6):2521-2525.
  6. Study of serum magnesium in type 2 diabetes mellitus and its correlation with the modality of treatment–a South Indian study. Int J Biomed Adv Res 2014;5(8):360-362.
  7. Insulin induces opposite changes in plasma and erythrocyte magnesium concentration in normal man. Diabetologia 1986 Sep;29(9):644-647.
  8. Study of serum magnesium and HbA1c in diabetic patients along with changes in their lipid profiles. Indian J Clin Pract 2013 Apr;23(11):717-719.
  9. A study of serum magnesium and dyspipidemia in type 2 diabetes mellitus patients. Int J Clin Biochem Res 2016;3(1):36-41.
  10. Lower serum magnesium levels are associated with rapid decline of renal function in patients with type 2 diabetes mellitus. Clin Nephrol 2005;63(6):429-436.
  11. Altered metabolism of copper, zinc and magnesium is associated with increased levels of glycated hemoglobin in patients with diabetes mellitus. Metabolism 2009 Oct;58(10):1477-1482.
  12. Significance of serum magnesium and electrolyte level in acute MI in first 6 hours. Pak J Cardiol 2006;17(1):25-29.
  13. Serum magnesium as a marker of diabetic complications. J Evol Med Dent Sci 2012 Sep;1(3):119-123.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.