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VOLUME 10 , ISSUE 1--4 ( January-December, 2024 ) > List of Articles

RESEARCH ARTICLE

Identification of Substance Abuse Using Urinary Kits: A Prospective Observational Study at a Tertiary Care Hospital

S Dwajani, Sahajananda Hiremathada

Keywords : Drug abuse, Substance abuse, Urine test

DOI: 10.5005/jp-journals-10045-00273

License: CC BY-NC 4.0

Published Online: 20-07-2024

Copyright Statement:  Copyright © 2024; The Author(s).


Abstract

Introduction: The epidemic of substance abuse (SA), which was previously common in Western populations, is now prevalent in India and is increasing, particularly among adolescents. Changing cultural values, increasing economic stress, and dwindling supportive bonds are leading to initiation into substance use. Random urine drug testing (UDT) is considered useful and is warranted for continued employment. Aim: To determine the pattern and extent of SA among patients and screen the suspect cases using UDT. Materials and methods: This was a prospective observational study. Subjects with a history of current substance use or suspected use for >10–30 days, seeking treatment for any medical reason related to substance use as diagnosed by the physician or psychiatrist, belonging to any age-group or gender, were included. The urine samples were collected and run on the multidrug cassettes to determine the results. Results: A total of 226 subjects were included, with 98.23% being male. The analysis for substance abuse was conducted using urine samples, and the results showed that the maximum number of subjects tested positive for cannabis/marijuana. The most frequent combination of substances abused was alcohol + tobacco + cannabis/marijuana (THC). Conclusion: According to the opinions presented in this study, the majority of patients who used THC and other psychoactive drugs were associated with stress, tiredness, and fatigue, which can impair judgment and coordination. There is a need for education, law enforcement, and frequent drug testing to regulate the supply of psychoactive chemicals. To increase acceptance and enhance results, it is crucial to incorporate policies and initiatives.


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  1. WHO. Techn. Res. Ser. No.886:1999. p. 48.
  2. Srivastava A, Pal HR, Dwivedi SN, et al. National household survey of drug abuse in India. Report submitted to the Indian Ministry of Social Justice and Empowerment and the United Nations Office for Drugs and Crime. 2003.
  3. Kumar MS. Rapid Assessment Survey of Drug Abuse in India. United Nations Office on Drugs and Crime Regional Office for South Asia and Ministry of Social Justice and Empowerment, Government of India. New Delhi, India. Available from [cited in 2002]: http://www.unodc.org/india/ras.html
  4. United Nations office on Drugs and Crime. World Drug Report 2009
  5. Management of substance abuse. The global burden. World health organization report. 2017. http://www.who.int/substance_abuse/facts/global_burden/en/. accessed on 13th June 2017
  6. Drug testing: a white paper of the American society of addiction medicine. October 26, 2013. American Society of Addiction. Medicine. https://www.asam.org/docs/default-source/public-policy-statements/drug-testing-a-white-paper-by-asam.pdf. accessed on 13th June 2017.
  7. Benegal V. India: alcohol and public health. Addiction 2005;100(8):1051–1056. DOI: 10.1111/j.1360-0443.2005.01176.x
  8. Nayak RB, Murthy P. Fetal alcohol spectrum disorder. Indian Pediatr 2008;45(12):977–983. PMID: 19129565.
  9. Agrawal A, Verweij KJH, Gillespie NA, et al. The genetics of addiction—a translational perspective. Transl Psychiatr 2012;2(7):e140. DOI: 10.1038/tp.2012.54
  10. Agrawal A, Wetherill L, Danielle MD, et al., Evidence for association between polymorphisms in the cannabinoid receptor 1(CNR1) gene and cannabis dependence. Am J Med Genet B Neuropsychiatr Genet 2009;150B(5):736–740. DOI: 10.1002/ajmg.b.30881
  11. Hartman CA, Hopfer CJ, Haberstick B, et al. The association between cannabinoid receptor 1 gene (CNR1) and cannabis dependence symptoms in adolescents and young adults. Drug Alcohol Depend 2009;104(1-2):11–16. DOI: 10.1016/j.drugalcdep.2009.01.022
  12. Sahu KK, Sahu S. Substance abuse causes and consequences. Bangabasi Acad J 2012.9:52–59.
  13. WHO. Substance abuse [cited 2022 16 Sept] Available from: http://www.who.int/topics/substance_abuse/en.
  14. Childline India Foundation. [cited 2022 16 Sept] Available from: http://www.childlineindia.org.in/cr-drug-abuse.htm.
  15. Ranganathan S, Jayaraman R, Thirumagal V, et al. Drug Addiction. Identification and Initial Motivation. A Field Guide for Service Providers and Trainers. Ministry of Social Justice & Empowerment, Govt. of India and United Nations International Drug Control Programme Regional Office for South Asia. 2002;3.
  16. Pratima Murthy S. Bala Shanthi Nikketha (Editors) Introduction in Psychosocial Interventions for Persons with Substance Abuse: Theory and Practice National Institute of Mental Health And Neuro Sciences (NIMHANS), Bangalore, India 2007;1.
  17. John A, Barman A, Bal D, et al. Hazardous alcohol use in rural southern India: nature, prevalence and risk factors. Natl Med J India 2009;22(3):123–125. PMID: 19764687.
  18. Mohan D, Chopra A, Sethi H. Incidence estimates of substance use disorders in a cohort from Delhi, India. Indian J Med Res 2002;115:128–135. PMID: 12201177.
  19. Longo, Lokan RJ, White JM, et al. Hunter: council of Europe. Role of alcohol, cannabinoids, Benzodiazepines and stimulants in road crashes. Alcohol, Drugs and Traffic Safety—T2000: Proceedings of the 15th International Conference on Alcohol, Drugs and Traffic Safety; International Council for Alcohol, Drugs & Traffic Safety 2000;363–374.
  20. Alti-Muazu M, Aliyu AA. Prevalence of psychoactive substance use among commercial motorcyclists and its health and social consequences in Zaria, Nigeria. Ann Afr Med 2008;7(2):67–71. DOI: 10.4103/1596-3519.55678
  21. Nkporbu AK, Stanley PC. A systematic review of pattern and prevalence of cannabis use among transporters and associated road traffic accidents. Int Neuropsy Dis J 2023;19(3):1–13. DOI: 10.9734/indj/2023/v19i3372
  22. WHO Management of. substance abuse: Facts and figures. [cited 2011;17 November] Available from: http://www.who.int/substance_abuse/facts/en.
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