Acute parotitis is a common clinical manifestation of various viral infections, metabolic and drug-related conditions. Parotitis is a relatively rare clinical manifestation of dengue fever. Mumps, parvovirus B19, Epstein–Barr virus, and coxsackievirus infections are the more common causative agents. We report a case of a 16-year-old kidney transplant recipient who presented with fever, chills, myalgia, and acute unilateral parotid swelling. He was detected to have dengue viremia in the saliva and blood. His course was complicated by parotid necrosis and was managed with antipyretics and antimicrobials with successful outcome. Parotitis is a rare manifestation of dengue fever. Parotitis along with leukopenia should arouse the suspicion of dengue infection, especially in endemic areas.
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