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VOLUME 10 , ISSUE 1--4 ( January-December, 2024 ) > List of Articles


Dengue Fever with Parotid Necrosis: A Case Report

Amit Katyal, Gaurav Vohra, Prasanthi Karam, Rajasekhar Vaka

Keywords : Case report, Dengue, Parotitis, Transplant

DOI: 10.5005/jp-journals-10045-00253

License: CC BY-NC 4.0

Published Online: 10-06-2024

Copyright Statement:  Copyright © 2024; The Author(s).


Acute parotitis is a common clinical manifestation of various viral infections, metabolic and drug-related conditions. Parotitis is a relatively rare clinical manifestation of dengue fever. Mumps, parvovirus B19, Epstein–Barr virus, and coxsackievirus infections are the more common causative agents. We report a case of a 16-year-old kidney transplant recipient who presented with fever, chills, myalgia, and acute unilateral parotid swelling. He was detected to have dengue viremia in the saliva and blood. His course was complicated by parotid necrosis and was managed with antipyretics and antimicrobials with successful outcome. Parotitis is a rare manifestation of dengue fever. Parotitis along with leukopenia should arouse the suspicion of dengue infection, especially in endemic areas.

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  1. Chauhan P, Gupta A, Mohan A, et al. Clinico-epidemiological study of an adult mumps outbreak in a naval training establishment. J Mar Med Soc 2018;20:138–140. DOI: 10.4103/jmms.jmms_20_18
  2. Dhochak N, Kabra SK, Lodha R. Dengue and chikungunya infections in children Indian J Pediatr 2019;86(3):287–295. DOI: 10.1007/s12098-018-2794-x
  3. Stanaway JD, Shepard DS, Undurraga EA, et al. The global burden of dengue: an analysis from the Global Burden of Disease Study 2013. Lancet Infect Dis 2016;16:712–723. DOI: 10.1016/S1473-3099(16)00026-8
  4. Chan M, Johansson MA. The incubation periods of dengue viruses. PLoS One 2012;7:e50972. DOI: 10.1371/journal.pone.0050972
  5. Pothapregada S, Kamalakannan B, Thulasingham M, et al. Clinically profiling pediatric patients with dengue. J Glob Infect Dis 2016;8:115–120. DOI: 10.4103/0974-777X.188596
  6. Pothapregada S, Kamalakannan B, Thulasingam M. Clinical profile of atypical manifestations of dengue fever. Indian J Pediatr 2016;83:493–499. DOI: 10.1007/s12098-015-1942-9
  7. Torres JR, Liprandi F, Goncalvez AP. Acute parotitis due to dengue virus. Clin Infect Dis 2000;31(5):e28–e29. DOI: 10.1086/317454
  8. Wasik D, Mulchandani A, Yates MV. Salivary detection of dengue virus NS1 protein with a label-free immunosensor for early dengue diagnosis. Sensors (Basel) 2018;18(8):2641. DOI: 10.3390/s18082641
  9. Sudiro TM, Ishiko H, Green S, et al. Rapid diagnosis of dengue viremia by reverse transcriptase-polymerase chain reaction using 3’-noncoding region universal primers. Am J Trop Med Hyg 1997;56:424–429. DOI: 10.4269/ajtmh.1997.56.424
  10. Lanciotti RS, Calisher CH, Gubler DJ, et al. Rapid detection and typing of dengue viruses from clinical samples by using reverse transcriptase-polymerase chain reaction. J Clin Microbiol 1992;30:545–551. DOI: 10.1128/jcm.30.3.545-551.1992
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