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VOLUME 10 , ISSUE 1--4 ( January-December, 2024 ) > List of Articles

REVIEW ARTICLE

A Brief Review on Anisocoria

Mary Stephen, P Jayasri

Keywords : Anisocoria, Dilator pupillae, Miosis, Mydriasis, Parasympathetic, Sphincter pupillae, Sympathetic

DOI: 10.5005/jp-journals-10045-00252

License: CC BY-NC 4.0

Published Online: 30-05-2024

Copyright Statement:  Copyright © 2024; The Author(s).


Abstract

Anisocoria is a medical condition where the pupils of the eyes are unequal in size. It stems from diverse causes such as neurological issues, eye injuries, medication side effects, or underlying medical conditions. Depending on the underlying cause, anisocoria can be benign or indicative of a serious health concern. Diagnosis typically involves a thorough examination of the eyes and may necessitate further neurological evaluation. Treatment strategies vary based on the specific cause and may involve addressing the underlying issue or managing symptoms to improve the condition.


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  1. McDougal DH, Gamlin PD. Autonomic control of the eye. Compr Physiol 2015;5(1):439–473. DOI: 10.1002/cphy.c140014
  2. Gross JR, McClelland CM, Lee MS. An approach to anisocoria. Curr Opin Ophthalmol 2016;27(6):486–492. DOI: 10.1097/ICU.0000000000000316
  3. Antonio-Santos AA, Santo RN, Eggenberger ER. Pharmacological testing of anisocoria. Expert Opin Pharmacother 2005;6(12):2007–2013. DOI: 10.1517/14656566.6.12.2007
  4. Wu L, Luo M, Jiang Y. Cortico-hypothalamic pathway of Horner syndrome derived from isolated lenticulostriate stroke. Clin Auton Res 2023;33(1):63–67. DOI: 10.1007/s10286-022-00914-w
  5. Martin TJ. Horner syndrome: a clinical review. ACS Chem Neurosci 2018;9(2):177–186. DOI: 10.1021/acschemneuro.7b00405
  6. Kanagalingam S, Miller NR. Horner syndrome: clinical perspectives. Eye Brain 2015;7:35–46. DOI: 10.2147/EB.S63633
  7. Kong YX, Wright G, Pesudovs K, et al. Horner syndrome. Clin Exp Optom 2007;90(5):336–344. DOI: 10.1111/j.1444-0938.2007.00177.x
  8. Mughal M, Longmuir R. Current pharmacologic testing for Horner syndrome. Curr Neurol Neurosci Rep 2009;9(5):384–389. DOI: 10.1007/s11910-009-0056-z
  9. Gao Z, Crompton JL. Horner syndrome: a practical approach to investigation and management. Asia Pac J Ophthalmol (Phila) 2012;1(3):175–179. DOI: 10.1097/APO.0b013e318256009d
  10. Nene AS, Pirdankar OH, Shah S, et al. Adie's tonic pupil: an uncommon ophthalmological emergency. Neurol India 2021;69(5):1487–1488. DOI: 10.4103/0028-3886.329525
  11. Yoo YJ, Hwang JM, Yang HK. Dilute pilocarpine test for diagnosis of Adie's tonic pupil. Sci Rep 2021;11(1):10089. DOI: 10.1038/s41598-021-89148-w
  12. Kanzaria HK, Farzan N, Coralic Z. Adie's tonic pupil. West J Emerg Med 2012;13(6):543. DOI: 10.5811/westjem.2012.7.12923
  13. Rendón Fernández H, Arias Del Peso B. Pupila tónica de Adie y otros signos asociados. Aten Primaria 2021;53(5):101982. DOI: 10.1016/j.aprim.2021.101982
  14. Koehler PJ, Wijdicks EF. Fixed and dilated: the history of a classic pupil abnormality. J Neurosurg 2015;122(2):453–463. DOI: 10.3171/2014.10.JNS14148
  15. Caglayan HZ, Colpak IA, Kansu T. A diagnostic challenge: dilated pupil. Curr Opin Ophthalmol 2013;24(6):550–557. DOI: 10.1097/ICU.0000000000000005
  16. Pupillary pathway. Am Acad Ophthalmol 2021;12(3).
  17. Payne WN, Blair K, Barrett MJ. Anisocoria. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024.
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